EBM Calculator

Evidence-Based Medicine diagnostic test calculator.

Features

• Sensitivity / Specificity calculation
• PPV / NPV with prevalence adjustment
• Likelihood ratios (LR+ / LR-)
• Number Needed to Treat (NNT)
• Pre/post-test probability conversion

Parameters

\* Required for diagnostic mode

\** Required for nnt mode

\* Required for probability mode

Output Format

{
  "sensitivity": "float",
  "specificity": "float",
  "ppv": "float",
  "npv": "float",
  "lr_positive": "float",
  "lr_negative": "float",
  "interpretation": "string"
}

Risk Assessment

Security Checklist

• [ ] No hardcoded credentials or API keys
• [ ] No unauthorized file system access (../)
• [ ] Output does not expose sensitive information
• [ ] Prompt injection protections in place
• [ ] Input file paths validated (no ../ traversal)
• [ ] Output directory restricted to workspace
• [ ] Script execution in sandboxed environment
• [ ] Error messages sanitized (no stack traces exposed)
• [ ] Dependencies audited

Prerequisites

No additional Python packages required.

Evaluation Criteria

Success Metrics

• [ ] Successfully executes main functionality
• [ ] Output meets quality standards
• [ ] Handles edge cases gracefully
• [ ] Performance is acceptable

Test Cases

1. Basic Functionality: Standard input → Expected output
2. Edge Case: Invalid input → Graceful error handling
3. Performance: Large dataset → Acceptable processing time

Lifecycle Status

• Current Stage: Draft
• Next Review Date: 2026-03-06
• Known Issues: None
• Planned Improvements:
• Performance optimization
• Additional feature support